Research Scientist/Engineer, Biological Safety
- Location
- San Francisco, CA
- Salary range
- USD $300,000 – $405,000 base
- Workplace
- Hybrid
- Level
- Individual contributor
- Job family
- Engineering
- Posted
- 9 months ago
The T&S Network estimates this role to be P4, Staff. The typical base salary for that level in Safety Engineering & Data Science is $330k to $420k at a frontier lab. Key skills at this level: owns a detection system end to end, including its drift and its retraining, designs for adversarial pressure rather than for a static distribution, and sets evaluation methodology others in the company adopt.
Why this level
Estimated from the posting rather than stated by the employer: asks for 8+ years · posts $300k to $405k base at a frontier lab · the title reads as P2.
The role, in T&S terms
Written by the T&S Network from Anthropic's posting.
Builds the safety and oversight mechanisms that govern how a frontier AI model handles biological knowledge. The work sits at the intersection of applied ML and biosecurity, covering capability evals, safety classifiers, and red-teaming of safeguards. The core problem is balancing robust protection against sophisticated bad actors with not blocking the much larger population of legitimate life sciences researchers.
What you'd do
- Design and run capability evaluations of new models in the biological domain and turn results into deployment recommendations
- Build training and evaluation datasets for safety classifiers with internal and external threat modeling experts
- Iterate on safety classifiers with ML engineers, balancing resistance to attacks against wrongly flagging benign use
- Measure classifier and eval results on live traffic, find weak spots, and rank fixes
- Probe safeguards with adversarial testing as threats and product surfaces shift
- Work with Research, Product, and Policy to build biological safety into model development
- Contribute to model cards, blog posts, and policy documents
What it asks for
- Strong Python and scientific programming with data analysis skills
- Excellent grasp of ML fundamentals and ability to adopt ML practices quickly
- Excellent knowledge of modern biology, including high-throughput assays, gene synthesis, genome editing, and protein engineering
- Can build and upkeep your own tooling without waiting on others
- Experience designing quantitative experiments and drawing conclusions from noisy results
- Working knowledge of dual-use and biosecurity rules, like select agent regulations, the BWC, or Australia Group lists
- Bachelor's degree or equivalent experience in a relevant field
Terms in this role
- Red teaming.
- Testing a system, often an AI model, by deliberately trying to make it fail or misbehave, so problems are found and fixed first.
Our best summary of the posting, and it can be wrong. The employer's posting is what counts: read it in full on Anthropic before you apply. If we got something wrong, report this listing.
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Still listed 14 hours ago
About Anthropic

The employer
About Anthropic
AI and model safety · San Francisco, CA · 1,001 to 5,000 people · Founded 2021
AI safety company building the Claude family of models.
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